The Framingham Heart Study (FHS) is an ongoing cohort study dedicated to identifying common factors or characteristics that contribute to cardiovascular disease (CVD). It is a collaborative project of the National Heart, Lung and Blood Institute and Boston University. In 1948, an original cohort of 5,209 men and women between 30 and 62 years old were recruited from Framingham, MA. An Offspring Cohort...

Action to Control Cardiovascular Risk in Diabetes (ACCORD) was a large clinical trial examining methods of lowering the rate of cardiovascular disease in adults with type two diabetes. The study was composed of three main clinical trials: an intensive lowering of blood sugar levels (Glycemia Trial), intensive lowering of blood pressure (Blood Pressure Trial), and treatment of multiple blood lipids...

Project AsPIRE (Asian American Partnership in Research and Endowment) was a community-based participatory research program designed to develop, test, and evaluate a community health worker model designed to reduce cardiovascular disease and hypertension disparities among Filipino Americans living in New York and New Jersey. The project consisted of a pilot intervention and a 4-month full intervention....

The Jackson Heart Study (JHS) is a population-based longitudinal study based in Jackson, Mississippi that investigates risk factors for cardiovascular disease among African Americans. It is a collaborative research project by the University of Mississippi Medical Center, Jackson State University, and Tougaloo College. The primary objective is to investigate environmental and genetic factors associated...

This dataset was generated as part of a cluster-randomized, 2-arm trial to evaluate the effectiveness of a faith-based group-counseling therapeutic lifestyle intervention and motivational interviewed (MINT-TLC) vs. health education (HE) on black adults who attend churches in New York City. 32 churches with approximately 300 eligible adults were randomly assigned to either MINT-TLC or HE control, and...

This dataset was generated from a 12-month two-arm cluster-randomized controlled trial, Counseling African Americans to Control Hypertension (CAATCH). The goal of the study was to evaluate the effectiveness of a multilevel, multicomponent, evidence-based intervention compared with usual care in improving blood pressure control among hypertensive blacks who receive care in community health centers....

The dataset includes a total of 757 patients with uncontrolled hypertension who were enrolled into the Task Shifting and Blood Pressure Control in Ghana (TASSH) study through 32 community health centers in Ghana. TASSH was a randomized controlled trial that compared the outcomes of 2 interventions to reduce systolic blood pressure (SBP): standard of care treatment available through public health insurance...

This study developed a scalable model for long-term vagus nerve stimulation (VNS) in mice. For this study, C57BL/6 mice were used in all experiments. The dataset includes histology and immunohistochemistry data as well as supplementary data tied to the publication. The supplementary data includes data that was used to assemble different figures in the publication, which contains data about heart rate...

The Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study examines risk factors for heart disease among South Asians of Indian, Pakistani, Bangladeshi, Nepali, and Sri Lankan descent in the United States to guide preventative measures and future treatments. Beginning in 2010, eligible South Asian participants between the ages of 40 and 80 were recruited from the San Francisco...